| W/L | Date | Opp. | Score | Record | Conf. Rec. |
|---|---|---|---|---|---|
| W | 11/09/21 | LoyolaMD | Won 83-67 | 1-0 | 0-0 |
| W | 11/12/21 | Brown | Won 94-87 | 2-0 | 0-0 |
| W | 11/16/21 | Col of C | Won 94-83 | 3-0 | 0-0 |
| L | 11/20/21 | #10 Purdue | Lost 84-93 | 3-1 | 0-0 |
| L | 11/21/21 | #5 Tennessee | Lost 72-89 | 3-2 | 0-0 |
| W | 11/23/21 | UNCAshe. | Won 72-53 | 4-2 | 0-0 |
| W | 12/01/21 | Michigan | Won 72-51 | 5-2 | 0-0 |
| W | 12/05/21 | GA Tech (ACC) | Won 79-62 | 6-2 | 1-0 |
| W | 12/11/21 | Elon | Won 80-63 | 7-2 | 1-0 |
| W | 12/14/21 | Furman | Won 74-61 | 8-2 | 1-0 |
| L | 12/18/21 | #7 Kentucky | Lost 69-98 | 8-3 | 1-0 |
| W | 12/21/21 | App.St. | Won 70-50 | 9-3 | 1-0 |
| W | 01/02/22 | Bos. Coll. (ACC) | Won 91-65 | 10-3 | 2-0 |
| L | 01/05/22 | Notre Dame (ACC) | Lost 73-78 | 10-4 | 2-1 |
| W | 01/08/22 | Virginia (ACC) | Won 74-58 | 11-4 | 3-1 |
| W | 01/15/22 | GA Tech (ACC) | Won 88-65 | 12-4 | 4-1 |
| L | 01/18/22 | MiamiFla (ACC) | Lost 57-85 | 12-5 | 4-2 |
| L | 01/22/22 | Wake Forest (ACC) | Lost 76-98 | 12-6 | 4-3 |
| W | 01/24/22 | Va Tech (ACC) | Won 78-68 | 13-6 | 5-3 |
| W | 01/26/22 | Bos. Coll. (ACC) | Won 58-47 | 14-6 | 6-3 |
| W | 01/29/22 | NC State (ACC) | Won 100-80 | 15-6 | 7-3 |
| W | 02/01/22 | Louisville (ACC) | Won 90-83 | 16-6 | 8-3 |
| L | 02/05/22 | #9 Duke (ACC) | Lost 67-87 | 16-7 | 8-4 |
| W | 02/08/22 | Clemson (ACC) | Won 79-77 | 17-7 | 9-4 |
| W | 02/12/22 | Fla.State (ACC) | Won 94-74 | 18-7 | 10-4 |
| L | 02/16/22 | Pitt (ACC) | Lost 67-76 | 18-8 | 10-5 |
| W | 02/19/22 | Va Tech (ACC) | Won 65-57 | 19-8 | 11-5 |
| W | 02/21/22 | Louisville (ACC) | Won 70-63 | 20-8 | 12-5 |
| W | 02/26/22 | NC State (ACC) | Won 84-74 | 21-8 | 13-5 |
| W | 02/28/22 | Syracuse (ACC) | Won 88-79 | 22-8 | 14-5 |
| W | 03/05/22 | #9 Duke (ACC) | Won 94-81 | 23-8 | 15-5 |
| W | 03/10/22 | Virginia (ACC) | Won 63-43 | 24-8 | 16-5 |
| L | 03/11/22 | Va Tech (ACC) | Lost 59-72 | 24-9 | 16-6 |
| W | 03/17/22 | Marquette | Won 95-63 | 25-9 | 16-6 |
| W | 03/19/22 | #4 Baylor | Won 93-86 | 26-9 | 16-6 |
| W | 03/25/22 | #11 UCLA | Won 73-66 | 27-9 | 16-6 |
| W | 03/27/22 | St. Peter's | Won 69-49 | 28-9 | 16-6 |
| W | 04/02/22 | #9 Duke (ACC) | Won 81-77 | 29-9 | 17-6 |
| L | 04/04/22 | #3 Kansas | Lost 69-72 | 29-10 | 17-6 |
Tournament History
| Year | Result |
|---|---|
| 2022 | National Finalist as #8 seed |
| 2021 | Lost First Round as #8 seed |
| 2019 | Sweet 16 as #1 seed |
| 2018 | Second Round as #2 seed |
| 2017 | National Champion as #1 seed |
| 2016 | National Finalist as #1 seed |
| 2015 | Sweet 16 as #4 seed |
| 2014 | Second Round as #6 seed |
| 2013 | Second Round as #8 seed |
| 2012 | Elite 8 as #1 seed |
| 2011 | Elite 8 as #2 seed |
| 2010 | -- |
| 2009 | National Champion as #1 seed |
| 2008 | Final Four as #1 seed |
| 2007 | Elite 8 as #1 seed |
| 2006 | Second Round as #3 seed |
| 2005 | National Champion as #1 seed |
| 2004 | Second Round as #6 seed |
| 2003 | -- |
| 2002 | -- |
| 2001 | Second Round as #2 seed |
| 2000 | Final Four as #8 seed |
| 1999 | Lost First Round as #3 seed |
| 1998 | Final Four as #1 seed |
| 1997 | Final Four as #1 seed |
| 1996 | Second Round as #6 seed |
| 1995 | Final Four as #2 seed |
| 1994 | Second Round as #1 seed |
| 1993 | National Champion as #1 seed |
| 1992 | Sweet 16 as #4 seed |
| 1991 | Final Four as #1 seed |
| 1990 | Sweet 16 as #8 seed |
| 1989 | Sweet 16 as #2 seed |
| 1988 | Elite 8 as #2 seed |
| 1987 | Elite 8 as #1 seed |
| 1986 | Sweet 16 as #3 seed |
| 1985 | Elite 8 as #2 seed |